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1.
BMC Med Educ ; 24(1): 446, 2024 Apr 24.
Artigo em Inglês | MEDLINE | ID: mdl-38658926

RESUMO

BACKGROUND: This research evaluated whether the relationships between factors of resilience, self-esteem, depression, and anxiety in dental students with changes in teaching and learning methods. We also studied the psychological impact of face-to-face lectures during the COVID-19 pandemic. METHODS: This cross-sectional descriptive study used Google Forms to collect data with the Rosenberg Self-Esteem Scale (RSE), Connor-Davidson Risk Resilience Scale (CD-RISC), Beck Anxiety Inventory (BAI), and Beck Depression Inventory (BDI and BDI-II). An open-ended question was also asked about important learning difficulties. RESULTS: The analysis revealed very high levels of resilience (30.23 ± 5.84), self-esteem in the normal range (29.08 ± 4.03), minimal depression levels (12.32 ± 8.05), and low anxiety levels (17.20 ± 12.41). There were no significant differences between sociodemographic variables ranges in regard to all psychological questionnaires. No high levels of depression and anxiety were found. CONCLUSIONS: The levels were low compared to other studies in which online teaching was used, which is explained by the fact that the students retained adequate resilience and self-esteem thanks to being able to contact teachers and, above all, their own peers.


Assuntos
Ansiedade , COVID-19 , Depressão , Resiliência Psicológica , Autoimagem , Estudantes de Odontologia , Humanos , COVID-19/epidemiologia , COVID-19/psicologia , Estudos Transversais , Estudantes de Odontologia/psicologia , Feminino , Masculino , Depressão/epidemiologia , Depressão/psicologia , Ansiedade/epidemiologia , Adulto Jovem , Adulto , Educação em Odontologia , Pandemias , Educação a Distância , SARS-CoV-2 , Inquéritos e Questionários
2.
Biomed Res Int ; 2022: 2739869, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36330456

RESUMO

The early detection of cancer, and in particular oral cancer, has been a priority objective of study in recent years. Saliva has been proposed as an easy-to-obtain means of providing the necessary information to diagnose malignant lesions in the oral cavity, since it can be obtained very easily and completely noninvasively. There are a number of molecules, known as biomarkers, which may be involved in the malignant transformation of oral lesions, and which have different natures. The involvement of proteins ("proteomics"), metabolites ("metabolomics"), and even certain genes in the structural changes of altered tissue has been investigated in order to establish validated parameters for the early diagnosis of oral cancer. In addition, the development of new analytical assay methods that can reduce costs and obtain better results in terms of sensitivity and specificity has been a key point in recent research in this field. Even though there are numerous biomarkers with results showing high sensitivity and specificity, there is still a need for more studies, with a larger sample and with analytical methods that can constitute a real advance in time and cost. Although salivary biomarkers are a promising new diagnostic tool for oral cancer, for the moment they do not replace biopsy as the "gold standard".


Assuntos
Neoplasias Bucais , Saliva , Humanos , Saliva/química , Neoplasias Bucais/diagnóstico , Neoplasias Bucais/metabolismo , Proteômica/métodos , Metabolômica , Biomarcadores/metabolismo , Biomarcadores Tumorais/metabolismo
4.
Nutrients ; 13(4)2021 Apr 15.
Artigo em Inglês | MEDLINE | ID: mdl-33920788

RESUMO

Oral cancer, included within head and neck cancer, is the sixth most common malignant neoplasm in the world. The main etiological factors are tobacco and alcohol, although currently, diet is considered an important determinant for its development. Several dietary nutrients have specific mechanisms of action, contributing to both protection against cancer and increasing the risk for development, growth, and spread. Foods such as fruits, vegetables, curcumin, and green tea can reduce the risk of oral cancer, while the so-called pro-inflammatory diet, rich in red meat and fried foods, can enhance the risk of occurrence. Dietary factors with a protective effect show different mechanisms that complement and overlap with antioxidant, anti-inflammatory, anti-angiogenic, and anti-proliferative effects. The main limitation of in vivo studies is the complexity of isolating the effects related to each one of the nutrients and the relationship with other possible etiological mechanisms. On the contrary, in vitro studies allow determining the specific mechanisms of action of some of the dietary compounds. In conclusion, and despite research limitations, the beneficial effects of a diet rich in vegetables and fruits are attributed to different micronutrients that are also found in fish and animal products. These compounds show antioxidant, anti-inflammatory, anti-angiogenic, and anti-proliferative properties that have a preventive role in the development of oral and other types of cancer.


Assuntos
Dieta Saudável/métodos , Dieta/efeitos adversos , Neoplasias Bucais/etiologia , Neoplasias Bucais/prevenção & controle , Animais , Neoplasias de Cabeça e Pescoço/etiologia , Neoplasias de Cabeça e Pescoço/prevenção & controle , Humanos , Fatores de Risco
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